Gunnery Sergeant Brandywine was a member of the United States Colonial Marine Corps. She was a small arms instructor in the mid-22nd Century. One of her pupils was a cadet Thomas A.W. Spears, with whom she had fraternized with. It is unknown what happened to Brandywine, except that her former pupil lamented that she would be approximately eighty years old had she not died, and that he would like to be with her one more time.
- Brandywine's name is a reference to Brandywine Productions, the company that produced the Alien film series.
- Aliens: Nightmare Asylum (appears in flashbacks)