- "Get to work, soldier."
- ―Sgt. Blackwell (from Aliens versus Predator 2)
In 2231, Blackwell was a member of the United States Colonial Marine Corps sent to LV-1201 aboard the USS Verloc. He is the leader of the squad tasked to get the landing beacon online after the Marines' dropship has a near crash-landing, leading Shugi and Harrison into the outer POC. After an explosion separates Harrison from his team, Blackwell reappears in the landing bay after Harrison activates the beacon and guides the dropship to its landing.
He is only seen sporadically for the rest of the Marine campaign, mainly cameoing in cutscenes. He is, however, seen in the final cutscene as one of the few Marine survivors of LV-1201, aboard the dropship along with Harrison, Shugi and Major McCain.
- John Armstrong, who voices Blackwell, also voices Dimitri and Duke Morrison in the game.
- In an occasional continuity error during the final Marine level, Blackwell and Shugi can sometimes be seen lying dead in the Queen's lair. The game's engine randomly selects Marine skins to portray the killed Marines in this level, and they forgot to remove Shugi and Blackwell as they are seen alive in the next cutscene.
- The phrase "Manos ariba" (the correct spelling would be manos arriba) written on Blackwell's chest plate armor means "Hands up!" in Spanish.