There are six weapons available to Colonial Marine characters. The player's sidearm in the game is permanently equipped and cannot be discarded. Up to two other weapons can be carried in addition to this, with the player able to switch these weapons out for new ones dependant on the situation or their personal preference. An exception is the M59/B Smartgun, which takes up both primary weapons slots, meaning any other weapons (apart from the player's pistol) must be discarded in order to use it.
W-Y VP78 Pistol
- Main article: VP78 Pistol
Armat M41A/2 Pulse Rifle
- Main article: M41A/2 Pulse Rifle
W-Y ZX-76 Shotgun
- Main article: ZX-76 Shotgun
Double barrel pump-action shotgun. Holds 8 rounds. Fires single shots as standard, but is also capable of unloading both barrels simultaneously for a devastating close-range blast.
Armat M42C Scoped Rifle
- Main article: M42C Scoped Rifle
Sniper/marksman rifle with a medium-powered scope. Holds 6 rounds. Incredibly powerful but limited by a slow rate of fire and high recoil.
- See: M56 Smartgun
Updated version of the M56 seen in Aliens. Incorporates an updated tracking system that no longer relies on infra-red allowing for the successful targeting of Xenomorph threats. Tracking systems can be toggled off for increased firepower at the cost of manual aiming. The Smartgun is not available in competitive multiplayer matches.
W-Y M260B Flamethrower
- Main article: M260B Flamethrower
Military-spec flamethrower. Capable of firing an unignited stream of fuel that can be lit subsequently to create a devastating wall of flame.
There are five weapons available to Predator characters. Unlike Marine weaponry, all of the available Predator weapons can be carried simultaneously (once discovered) and as such cannot be discarded.
- Main article: Wrist Blades
All Predators use this lethal blades in both hands, the wrist blade its a deadly weapon in the hands of a expert hunter this blades are powerfull enough to decapitate both human and Xenomorph species. also can do a lethal finishing moves with it.
- Main article: Plasma Caster
Another of the main weapons of the Hunter, the Plasma Caster its a lethal laser weapon, only need a little energy to produce masive damage to the human and xenomorph prey.
- Main article: Smart-Disc
In the hands of real hunters this weapon can do a masive damage to the enemy. with the same edge of the Marines combat Knife even more. the Smart-Disc can destroy simple metalic objects.
- Main article: Predator Mines
With the same technology of the Plasma Caster , The Predator Mines are really usefull to suprise or ambush the enemy.
- Main article: Combi-Stick
This weapon used by the most powerfull warriors in the right hands, this spear can easily kill the enemy with a single shot.