Alien vs. Predator vs. Evangelion.
The Story is all of Evangelion (OG show + End of Eva; no Rebuild), but the characters are Yautja/Predators mostly. They must use giant cyborgs called Evangelions or Evas to fight large armies of Xenomorphs and god-like aliens called Angels, defending Yautja Prime, which was hit by two extinction events called "Impacts," with a third one on the way if the angels are not defeated. The final angel is an angelic Predalien called Tabris, who is defeated by Predator Shinji. Eventually, the Predators begin their plans for the Third Impact. Predator Gendo gets the artificially tame Xenomorph who was forced to pilot one of the Eva, to begin the Third Impact, revealing that the entire Yautja and Xenomorph species are the children of Lilith, a Giant Xenomorph/Angel hybrid who was contained deep under the planet's surface. The Xenomorph betrays Predator Gendo, and merges with Lilith. The Xenomorph Deity breaks out and Predator Shinji is forced to bear witness the giant glowing Xenomorph. After an acid trip of sorts, Predator Shinji commands Lilith to begin the Third Impact, which merges all of the Predators and Xenomorphs' souls into a single mass in the form of turning into the primordial soup called LCL. After realising that life is worth living, Predator Shinji rejects the Third Impact's salvation, and re-materializes himself as Lilith dies, falling apart and ending the impact.
That's just my idea on how it would go. Sorry you had to bear witness the cringe, not to mention I'm not a big Eva fan but everyone seems to talk about it.